Thermo Fisher Scientific CD300e Monoclonal Antibody (233810)
CD300e 단백질을 인식하는 Rat IgG2a 단클론 항체로, Western blot 및 유세포분석에 적합합니다. 인간 시료 반응성이 있으며, Protein A/G로 정제된 동결건조 형태입니다. CD300e 신호전달 연구 및 면역세포 활성화 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 233810 |
| Immunogen | Y3 rat myeloid cell line transfected with human CD300e/LMIR6 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607573 |
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human LMIR1, 2, 3, 4, or 5 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is downregulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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