Thermo Fisher Scientific CD300e Monoclonal Antibody (233810)

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL

Flow Cytometry (Flow)

• Tested Dilution: 2.5 µg per million cells

Product Specifications

Product Specific Information

In direct ELISAs, no cross-reactivity with recombinant human LMIR1, 2, 3, 4, or 5 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is downregulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.