Thermo Fisher Scientific PPP3CC Polyclonal Antibody
PPP3CC 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human·Mouse·Rat에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific PPP3CC Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PPP3CC (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca²⁺-dependent modifier of phosphorylation status. In testis, sperm motility is thought to be controlled by cAMP-dependent phosphorylation, and a unique form of calcineurin is associated with the flagellum. The calcineurin holoenzyme comprises catalytic and regulatory subunits of 60 and 18 kDa, respectively. At least three genes—calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3)—encode the catalytic subunit, identified in humans, mice, and rats, showing high conservation (90–95% amino acid identity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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