Thermo Fisher Scientific POLR1B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 670-900 of human POLR1B (NP_0618872) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:POLR1B,uniProtId:Q9H9Y6-1,ncbiNodeId:9606,antigenRange:670-900,antigenLength:1135,antigenImageFileName:PA5-88309_POLR1B_Q9H9Y6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88309_POLR1B_Q9H9Y6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.65 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804819

Product Specific Information

Immunogen sequence: IANFIPFSDH NQSPRNMYQC QMGKQTMGFP LLTYQDRSDN KLYRLQTPQS PLVRPSMYDY YDMDNYPIGT NAIVAVISYT GYDMEDAMIV NKASWERGFA HGSVYKSEFI DLSEKIKQGD SSLVFGIKPG DPRVLQKLDD DGLPFIGAKL QYGDPYYSYL NLNTGESFVM YYKSKENCVV DNIKVCSNDT GSGKFKCVCI TMRVPRNPTI GDKFASRHGQ KGILSRLWPA E; Positive Samples: HeLa, HT-29, 293T, Mouse spleen; Cellular Location: Nucleus, nucleolus

Target Information

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.