Thermo Fisher Scientific POLR1B Polyclonal Antibody
POLR1B 단백질을 인식하는 Thermo Fisher의 rabbit polyclonal 항체로, WB 및 ELISA에 최적화되어 있습니다. 인간 및 생쥐 시료에 반응하며, 핵 및 인(nucleolus)에서 발현되는 POLR1B 단백질 검출에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 670–900 of human POLR1B (NP_0618872) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804819 |
Product Specific Information
Immunogen sequence:
IANFIPFSDH NQSPRNMYQC QMGKQTMGFP LLTYQDRSDN KLYRLQTPQS PLVRPSMYDY YDMDNYPIGT NAIVAVISYT GYDMEDAMIV NKASWERGFA HGSVYKSEFI DLSEKIKQGD SSLVFGIKPG DPRVLQKLDD DGLPFIGAKL QYGDPYYSYL NLNTGESFVM YYKSKENCVV DNIKVCSNDT GSGKFKCVCI TMRVPRNPTI GDKFASRHGQ KGILSRLWPA E
Positive Samples: HeLa, HT-29, 293T, Mouse spleen
Cellular Location: Nucleus, nucleolus
Target Information
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the two largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996).
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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