Thermo Fisher Scientific NOVA1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NOVA1 protein for Western blot and ELISA applications. Recognizes neuron-specific RNA-binding protein involved in paraneoplastic disease. Supplied as liquid, affinity purified, unconjugated, and stored at -20°C.
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Thermo Fisher Scientific NOVA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 408–507 of human NOVA1 (NP_0025062) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.12 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804817 |
Product Specific Information
- Immunogen sequence: SAILGTEKST DGSKDVVEIA VPENLVGAIL GKGGKTLVEY QELTGARIQI SKKGEFVPGT RNRKVTITGT PAATQAAQYL ITQRITYEQG VRAANPQKVG
- Positive Samples: U-251MG, SH-SY5Y
- Cellular Location: Nucleus
Target Information
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens. It is recognized and inhibited by paraneoplastic antibodies found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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