Thermo Fisher Scientific SEMA7A Polyclonal Antibody
인간 SEMA7A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. 세포막 및 GPI-앵커 단백질 검출에 유용하며, 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 45–280 of human SEMA7A (NP_003603.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804821 |
Product Specific Information
Immunogen sequence:
QGHLRSGPRI FAVWKGHVGQ DRVDFGQTEP HTVLFHEPGS SSVWVGGRGK VYLFDFPEGK NASVRTVNIG STKGSCLDKR DCENYITLLE RRSEGLLACG TNARHPSCWN LVNGTVVPLG EMRGYAPFSP DENSLVLFEG DEVYSTIRKQ EYNGKIPRFR RIRGESELYT SDTVMQNPQF IKATIVHQDQ AYDDKIYYFF REDNPDKNPE APLNVSRVAQ LCRGDQGGES SLSVSK
Positive Samples: A549, HT-29, Raji
Cellular Location: Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor
Target Information
CD108 (Sema7A) is a GPI-anchored semaphorin family member that enhances central and peripheral axonal growth and is required for proper axon track formation during embryogenesis.
It regulates osteoclast differentiation and pre-osteoblastic cell migration, and in the immune system affects cell proliferation, chemotaxis, and cytokine release.
On erythrocytes, CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signals through its receptors—plexin C1 and beta1 integrins.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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