
Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
SLC6A8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(F)에서 검증됨. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며, -20°C에서 보관 권장.
- 카탈로그번호
- AGT-008-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SLC6A8 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RLAVPPRETWTRQMD, corresponding to amino acid residues 46–60 of rat creatine transporter, Extracellular, C-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution:
- 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- Ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT, or CRTR, is a 635-amino-acid multi-pass plasma membrane protein belonging to the sodium/neurotransmitter (SNF) family.
It is expressed in various tissues including kidney, skeletal muscle, heart, brain, prostate, testis, and colon.
SLC6A8 functions to transport creatine into and out of cells, particularly in brain and muscle tissues.
Creatine is essential for energy supply in muscle and nerve function.
Defects in SLC6A8 cause cerebral creatine deficiency and X-linked creatine deficiency syndrome, characterized by facial anomalies, seizures, and mental retardation.
Multiple isoforms exist due to alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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