Thermo Fisher Scientific TMEM204 Monoclonal Antibody (652424)
TMEM204 단백질을 인식하는 Mouse IgG2b 단일클론 항체. 면역세포화학(ICC/IF) 및 유세포분석(Flow Cytometry)에 적합. 단백질 A/G로 정제된 동결건조 형태로 제공되며, 인체 유래 TMEM204 단백질 연구용. 저산소 조건에서 발현되는 세포 접착 관련 단백질 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 652424 |
| Immunogen | NS0 mouse myeloma cell line transfected with human CLP24 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605738 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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