Thermo Fisher Scientific TSPAN8 Monoclonal Antibody (657909)
마우스 TSPAN8 단백질을 특이적으로 인식하는 Rat IgG2b 단클론 항체입니다. IHC, IHC(F), Flow Cytometry에 적합하며, 단백질 A/G로 정제된 동결건조 형태로 제공됩니다. 암 관련 신호전달 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 8–25 µg/mL | - |
| Flow Cytometry (Flow) | 2.5 µg per million cells | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 657909 |
| Immunogen | CHO Chinese hamster ovary cell line transfected with mouse TSPAN8 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606498 |
Product Specific Information
This antibody detects mouse TSPAN8 transfectants but not the parental cell line in flow cytometry.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237-amino-acid multi-pass membrane protein belonging to the tetraspanin family. It plays a role in signal transduction influencing cell development, activation, growth, and motility.
Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal, and pancreatic cancers, suggesting involvement in cancer formation and metastasis.
The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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