Thermo Fisher Scientific CK8 Polyclonal Antibody
다양한 응용 분야(WB, IHC, ICC, Flow, ELISA)에 적합한 CK8 폴리클로날 항체. Rabbit IgG 기반으로 Human, Mouse, Rat, Chicken 반응성. 단백질 A로 정제된 고순도 항체로 세포 구조 및 신호전달 연구에 활용 가능.
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Thermo Fisher Scientific CK8 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CK8, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 8 is a member of the type II keratin family located on chromosome 12. Type I and type II keratins heteropolymerize to form intermediate filaments in epithelial cells. CK8 typically dimerizes with keratin 18 to form filaments in simple epithelial cells. This protein contributes to cellular structural integrity, signal transduction, and differentiation. Mutations in this gene are associated with cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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