Thermo Fisher Scientific CTLA-4 Polyclonal Antibody
CTLA-4 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 마우스 시료에 반응. Western blot과 IHC에 적합하며 높은 특이성과 재현성을 제공. 연구용으로 면역조절 관련 단백질 분석에 활용 가능.
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Thermo Fisher Scientific CTLA-4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CTLA4 (Accession P16410), corresponding to amino acid residues K130–L180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899696 |
Product Specific Information
This antibody detects endogenous levels of total CTLA4.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds to the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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