Thermo Fisher Scientific CSF2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total CSF2.

Target Information

The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form exists as a homodimer in the extracellular space. This gene cluster on chromosome 5q31 is associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia. Other genes in this region include interleukins 4, 5, and 13. The GM-CSF gene is involved in promoting tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.