Thermo Fisher Scientific Lubricin Polyclonal Antibody
Thermo Fisher Scientific의 Lubricin Polyclonal Antibody는 인간 Lubricin 단백질을 검출하는 고품질 항체로, Western blot 및 면역조직화학에 적합합니다. Rabbit IgG 폴리클로날 형태이며, PBS/BSA 버퍼에 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 3 publications |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Horse, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2169239 |
Product Specific Information
PA3-118 detects Lubricin in human samples.
It has been successfully used in Western blot procedures and detects a 280 kDa protein representing recombinant human Lubricin.
This antibody performs best on purified or recombinant samples under non-reducing conditions.
Immunogen is a synthetic peptide corresponding to residues C L(1356) P N I R K Q P D G Y D Y Y A F S K D Q(1374) of human Lubricin.
This polyclonal antibody has been referred to as JSCLPN.
Target Information
Lubricin is a glycoprotein encoded by the PRG4 gene. It functions in joint lubrication and synovial homeostasis by reducing friction and preventing synovial cell overgrowth.
It is a large, water-soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL).
Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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