
Thermo Fisher Scientific SPINK5 Recombinant Rabbit Monoclonal Antibody (23GB4180)
SPINK5 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot 및 ICC/IF 실험에 적합하며, 높은 특이성과 재현성을 제공. 인간, 마우스, 랫트 시료에 반응하며, HEK293F 발현 시스템에서 생산된 액상 형태 항체.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
- Immunocytochemistry (ICC/IF): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4180 |
| Immunogen | A synthesized peptide derived from human SPINK5/LEKTI (150–200AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Lympho-epithelial Kazal-type inhibitor (LEKTI) is a serine protease inhibitor that protects mucous epithelia against microbial attack and inflammation. LEKTI serves as a marker of epithelial differentiation and is strongly expressed in the granular and uppermost spinous layers of the epidermis and differentiated layers of stratified epithelia.
Defects in SPINK5, the gene encoding LEKTI, cause Netherton syndrome, a severe autosomal recessive disorder characterized by atopic dermatitis, hayfever, and related conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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