Thermo Fisher Scientific SNAP23 Polyclonal Antibody
SNAP23 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat에 반응하며 고순도 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SNAP23 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 4 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | – |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Bovine, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: C N(193) K N R I D I A N T R A K K L I D S(210) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2192025 |
Product Specific Information
PA1-738 detects synaptosomal-associated protein 23 (SNAP-23) from human, mouse, and rat samples.
It has been successfully used in Western blot and immunoprecipitation procedures.
By Western blot, this antibody detects an approximately 23 kDa protein representing SNAP-23 from rat/mouse brain protein extract and HeLa cell lysates.
The immunizing peptide corresponds to amino acid residues 193–210 from mouse SNAP-23 protein.
PA1-738 immunizing peptide (Cat. # PEP-147) is available for use in neutralization and control experiments.
Target Information
Specificity of vesicular transport is regulated by the interaction between vesicle-associated membrane proteins (synaptobrevin/VAMP) and target membrane proteins (syntaxin).
Together with SNAP25, these proteins form a complex that acts as a binding site for the membrane fusion machinery.
Synaptobrevin/VAMP and syntaxin are involved in vesicular transport in most cells, while SNAP25 is largely brain-specific.
SNAP23, a homolog of SNAP25, is ubiquitously expressed and facilitates vesicle docking and fusion in other tissues.
It binds tightly to multiple syntaxins and synaptobrevins/VAMPs, acting as an essential component of the high-affinity receptor for membrane fusion machinery.
Two alternative transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.