Thermo Fisher Scientific Human SRPX Synthetic Peptide
인간 SRPX1의 N-말단 13개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-20843 항체의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 PBS 버퍼에 보관되며, 연구용으로 적합합니다. 암세포 및 자가포식 관련 연구에 활용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the amino terminus of human SRPX1.
PEP-0957 can be used as a blocking peptide with polyclonal antibody PA5-20843.
Target Information
SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye under glaucoma conditions.
Its expression is significantly downregulated in several cancer cell lines and malignant tumor tissues. Ectopic expression induces apoptosis through the endoplasmic reticulum and activation of caspase-12, -9, and -3, suggesting a tumor suppressor role.
SRPX1 also participates in the regulation of autophagy under low serum conditions and associates with Rab24, a Rab GTPase family member involved in autophagy. This association is enhanced during autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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