Thermo Fisher Scientific Human TMEM16B Synthetic Peptide
Human TMEM16B 단백질의 아미노 말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드로, 항체 PA5-20842의 차단용 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS(pH 7.2, 0.1% BSA) 용액에 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the amino terminus of human TMEM16B.
PEP-0956 can be used as a blocking peptide with polyclonal antibody PA5-20842.
Target Information
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCCs include the transmembrane proteins TMEM16A and TMEM16B.
TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina.
Like TMEM16A, TMEM16B is thought to form at least part of CaCCs but has different biophysical characteristics such as voltage dependence and unitary conductance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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