Thermo Fisher Scientific Human SRPX2 Synthetic Peptide
인간 SRPX2 단백질의 N-말단 16 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-20844 항체의 블로킹 펩타이드로 사용 가능합니다. 혈관신생 및 암 전이 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human SRPX2.
PEP-0958 can be used as a blocking peptide with polyclonal antibody PA5-20844.
Target Information
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain. Mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation, and cognitive disorders.
Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, facilitating invasive migration of sprouting endothelial cells.
SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion. These findings suggest SRPX2 may be a potential target in the treatment of metastatic cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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