Thermo Fisher Scientific Kappa Light Chain/IGKC Recombinant Rabbit Monoclonal Antibody (KLC2289R)
인간 Kappa Light Chain(IGKC)을 타겟으로 하는 Thermo Fisher의 재조합 래빗 모노클로날 항체입니다. IHC(P) 실험에 적합하며, 높은 특이성과 재현성을 제공합니다. 단백질 A/G로 정제된 액상 형태이며, 보존제가 포함되어 있지 않습니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KLC2289R |
| Immunogen | Recombinant full-length human Ig kappa chain (IGKC) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Immunoglobulin classes share the same basic structure of two heavy chains and two light chains (kappa, lambda; both ~22.5 kDa).
Kappa and lambda chains consist of variable and constant regions and are differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is approximately 70:30.
Antibodies to the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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