Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI3B5), TrueMAB
CDCA7L 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI3B5). Western blot 및 IHC(Paraffin)에 적합하며, Human 시료에 반응. 액상 형태로 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of human CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter region. CDCA7L also plays an oncogenic role by mediating the transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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