Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI4A2), TrueMAB
CDCA7L 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 인간 유래 재조합 단백질(aa 1-337)을 면역원으로 사용하며, 비결합형 액상 형태입니다. 1 mg/mL 농도로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of human CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways.
It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter.
CDCA7L plays an oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells and may function downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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