Thermo Fisher Scientific URM1 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
SVEVEFGGGAE LLFDGIKKHR VTLPGQEEPW DIRNLLIWIK KNLLKERPEL FIQGDSVRPG ILVLINDADW ELLGELDYQL QDQDSVLFIS TLHG

Highest antigen sequence identity to the following orthologs:

• Mouse: 93%
• Rat: 94%

Target Information

Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, which include SUMO, ISG15, Nedd8, and Atg8, function as critical regulators of many cellular processes, including transcription, DNA repair, signal transduction, autophagy, and cell-cycle control.
A growing body of data also implicates the dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery in the etiology and progression of a number of human diseases.
URM1 is a ubiquitin-like modifier protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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