Thermo Fisher Scientific CCDC36 Monoclonal Antibody (OTI5E11), TrueMAB
인간 CCDC36 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot에 최적화된 TrueMAB 제품으로, 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며, 재구성 및 접합 실험에 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CCDC36 Monoclonal Antibody (OTI5E11), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Publications: [References not available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E11 |
| Immunogen | Full length human recombinant protein of human CCDC36 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination.
Likely forms a complex with MEI4 and REC114, activating DSBs formation in unsynapsed regions—an essential step for synapsis completion.
Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC), or meiotic surveillance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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