Thermo Fisher Scientific CD13 Polyclonal Antibody
CD13 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간·마우스·랫트 시료에 반응합니다. IHC(P) 및 Flow Cytometry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 0.5 mg/mL 농도, 4°C 또는 -20°C 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from C-terminus of human CD13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Kidney
- Cellular location: Membrane and cytoplasm
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It functions as a metalloprotease that removes neutral amino acids from small peptides, regulating activation or inactivation of bioactive peptides.
CD13 plays roles in extracellular matrix degradation, antigen processing, signal transduction, inflammatory responses, intercellular contact regulation, cell motility, and vascularization.
It is expressed by granulocytes, monocytes, and myeloid leukemia cells, contributing to leukemic cell protection against apoptosis and poor carcinoma prognosis.
Additionally, CD13 acts as an aminopeptidase enzyme and alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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