Thermo Fisher Scientific Human TIAF1 Synthetic Peptide
Human TIAF1 단백질의 N-말단 16 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-34538과 함께 블로킹 펩타이드로 사용 가능. Western blot 등 연구용으로 적합하며, PBS 완충액에 보관. -20°C에서 안정적으로 저장.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human TIAF.
PEP-1581 can be used as a blocking peptide with polyclonal antibody PA5-34538.
For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Target Information
TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that inhibits the cytotoxic effects of TNF-alpha, TRADD, and FADD.
It localizes to the nucleus and is significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection.
Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation.
TIAF1 is essential in p53- and WOX1-mediated cell death and shows aggregation-dependent control of tumor progression, metastasis, and regulation of cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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