Thermo Fisher Scientific AMPK gamma-1 Monoclonal Antibody (4A1G9)
AMPK gamma-1 단백질을 인식하는 Mouse Monoclonal 항체로, Western blot, IHC, ELISA에 사용 가능. Human 시료에 반응하며, Protein G 정제 및 PBS buffer에 0.05% sodium azide 포함. 연구용으로 에너지 대사 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A1G9 |
| Immunogen | Purified recombinant fragment of human PRKAG1 (AA: 230–331) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787490 |
Product Specific Information
MA5-31867 has been tested in indirect ELISA.
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It functions as an energy-sensing enzyme that monitors cellular energy status. Upon metabolic stress, AMPK is activated and phosphorylates enzymes such as acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), which are key regulators of fatty acid and cholesterol biosynthesis. This antibody targets one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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