Thermo Fisher Scientific CD137 (TNFRSF9) Monoclonal Antibody (OTI3B8)
인간 CD137(TNFRSF9)을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. HEK293T 세포에서 발현된 재조합 단백질을 면역원으로 사용하였으며, PBS/50% glycerol/1% BSA buffer에 보관됩니다. 연구용 전용 제품입니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B8 |
| Immunogen | Full length human recombinant protein of human TNFRSF9 (NP_001552) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling contributes to the survival and expansion of activated and memory T cells, while regulating myelopoiesis and dendritic cell development. Triggered CD137 induces cytokine release that influences peripheral monocyte survival. Soluble CD137 may act as a negative regulator in immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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