Thermo Fisher Scientific Phospho-RBM4 (Ser309) Polyclonal Antibody, FITC
인산화된 RBM4(Ser309)을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PRBM4-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Phospho-RBM4 (Ser309) Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated synthetic peptide within amino acid region 300–350 of human RNA binding motif protein 4 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8), containing 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RNA-binding factor involved in multiple aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation.
Modulates alternative 5′ splice site and exon selection, acts as a muscle cell differentiation-promoting factor, and activates exon skipping of PTB pre-mRNA during muscle cell differentiation.
Antagonizes PTBP1 activity to modulate muscle cell-specific exon selection of alpha-tropomyosin.
Binds intronic pyrimidine-rich sequences of TPM1 and MAPT pre-mRNAs, and is required for translational activation of PER1 mRNA in response to the circadian clock.
Exerts suppressive activity on cap-dependent translation via CU-rich elements within the 3′UTR, increased under stress or during myocyte differentiation.
Recruits EIF4A1 for IRES-dependent translation initiation under stress conditions and associates with AGO2-containing miRNPs for miRNA-guided RNA cleavage and translation suppression.
Binds preferentially to the 5′-CGCGCG[GCA]-3′ motif in vitro.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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