
Thermo Fisher Scientific AURKC Monoclonal Antibody (OTI2B7), TrueMAB
인간 AURKC 단백질을 인식하는 마우스 모노클로날 항체로 Western blot에 적합합니다. 동결건조 형태이며 PBS 버퍼에 8% 트레할로스를 포함, 보존제가 없습니다. 세포 분열 및 암 관련 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Full-length human AURKC protein expressed in 293T cells transfected with human AURKC expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins. It plays a crucial role in organizing microtubules related to centrosome/spindle function during mitosis.
AURKC is overexpressed in several cancer cell lines, suggesting involvement in oncogenic signaling.
Aurora kinases are associated with mitotic structures and influence key cell cycle events such as centrosome duplication, chromosome segregation, and cytokinesis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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