Thermo Fisher Scientific FANCC Monoclonal Antibody (OTI11B2), TrueMAB
인간 FANCC 단백질(aa 1-284)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 적합하며, 동결건조 형태로 제공. PBS 완충액(8% 트레할로스) 포함, 방부제 없음. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–284 of human FANCC produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder associated with cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
FANCC encodes a protein that is part of the common nuclear protein complex involved in the Fanconi anemia pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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