Thermo Fisher Scientific Nerve growth factor inducible Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합한 Rabbit Polyclonal 항체. Human, Mouse, Rat 반응성. KLH 결합 합성 펩타이드(aa 451-550)로부터 유래. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human VGF/Nerve growth factor inducible, amino acids 451–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. It is synthesized in neurons in the central and peripheral nervous system, as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in energy balance and homeostasis regulation. Mice lacking this gene show deficits in these areas. Recent studies suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like effects, indicating potential therapeutic relevance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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