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Thermo Fisher Scientific Adenylosuccinate Lyase Polyclonal Antibody
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Adenylosuccinate Lyase 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 04:27
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Thermo Fisher Scientific BS-6352R Adenylosuccinate Lyase Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
531,800원VAT 포함 584,980원
Thermo Fisher Scientific · Thermo Fisher Scientific Adenylosuccinate Lyase Polyclonal Antibody
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase (amino acids 185–280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein involved in purine biosynthesis and AMP formation from inosine monophosphate. It catalyzes two key reactions in AMP biosynthesis:
- Removal of fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to form aminoimidazole carboxamide ribotide (AICA)
- Removal of fumarate from adenylosuccinate to yield AMP
Defects in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder characterized by epilepsy, growth retardation, and muscular wasting. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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