Thermo Fisher Scientific KCNQ4 Polyclonal Antibody
KCNQ4 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드(aa 601-613)를 면역원으로 사용하며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다. 인체 시료에 반응하며, 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DKGPSDAEVVDE) corresponding to the internal amino acids of KCNQ4 (aa 601–613) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10985466 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
The protein encoded by this gene forms a potassium channel that plays a critical role in regulating neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the KCNQ3 gene. Defects in this gene are associated with nonsyndromic sensorineural deafness type 2, an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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