Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI1E2), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution

• 1:2,000

Publications

• [References not provided]

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and contributes to their suppressive function.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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