Thermo Fisher Scientific MTPN Monoclonal Antibody (1F3)
MTPN 단백질을 인식하는 마우스 단클론 항체(1F3)로, Western blot, ICC/IF, ELISA 등에 사용 가능. 인간 단백질에 반응하며 비결합(Unconjugated) 형태로 제공. PBS(pH 7.4) 용액 상태로 -20°C에서 보관.
- 카탈로그번호
- H00136319-M14
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F3 |
| Immunogen | MTPN (AAH28093, 1–118 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MCDKEFMWAL KNGGLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ
Target Information
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6.
The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFκB p50–p65 heterodimers to p50–p50 and p65–p65 homodimers.
This protein also has a potential function in cerebellar morphogenesis and may be involved in the differentiation of cerebellar neurons, particularly granule cells.
A cryptic ORF at the 3′ end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen associated with myeloproliferative disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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