Thermo Fisher Scientific MTPN Polyclonal Antibody, MaxPab
MTPN 단백질을 인식하는 다클론 항체로 Western blot 및 면역세포염색에 적합. Human 시료에 반응하며 PBS 용액 형태로 제공. 친화 크로마토그래피로 정제되어 고순도 확보. 연구용으로 심장비대 및 신경분화 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MTPN (NP_665807.1, 1–118 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ
Target Information
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6.
The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFκB p50-p65 heterodimers to p50-p50 and p65-p65 homodimers.
This protein may also function in cerebellar morphogenesis and neuronal differentiation, particularly of granule cells.
A cryptic ORF at the 3′ end of this transcript uses an internal ribosome entry site and a non-AUG initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen associated with myeloproliferative disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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