Thermo Fisher Scientific UNC5D Monoclonal Antibody (4G3)
UNC5D 단백질을 인식하는 Mouse monoclonal antibody(클론 4G3)로, Western blot과 ELISA에 적합합니다. 인간 시료에 반응하며, PBS(pH 7.4) 용액 상태로 제공됩니다. 순도 높은 Affinity chromatography 정제 제품으로 연구용에 적합합니다.
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- H00137970-M01
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G3 |
| Immunogen | UNC5D (NP_543148, 31 a.a. ~130 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
TDNGEALPES IPSAPGTLPH FIEEPDDAYI IKSNPIALRC KARPAMQIFF KCNGEWVHQN EHVSEETLDE SSGLKVREVF INVTRQQVED FHGPEDYWCQ
Target Information
UNC5D (also known as KIAA1777, UNC5H4) is a receptor for netrin and belongs to the unc-5 family. It plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. The repulsion may result from its association with DCC, triggering repulsion signaling. Additionally, UNC5D acts as a dependence receptor required for apoptosis induction when unbound to netrin ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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