Thermo Fisher Scientific CD3d Polyclonal Antibody
Human CD3D 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ELISA, IP에 적합합니다. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. T세포 수용체 복합체 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CD3D protein (Met1–Ala105) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787749 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CD3D.
Target Information
CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction.
The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells.
Defects in the CD3d gene cause severe combined immunodeficiency (autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive, SCIDBNK).
Two transcript variants encoding different isoforms of CD3d have been found. Other variants may also exist, but their full-length transcripts have yet to be defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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