Thermo Fisher Scientific IRAK-M Polyclonal Antibody
IRAK-M 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot과 Immunocytochemistry에 사용 가능하며, Human 및 Non-human primate에 반응합니다. Protein A로 정제된 액상 형태로, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy-terminus of human IRAK-M |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 29 µg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986892 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
IRAK3 (Interleukin-1 receptor-associated kinase 3) is a serine/threonine kinase and a member of the IRAK protein family, essential in Toll/IL-R immune signal transduction pathways.
It is primarily expressed in monocytes and macrophages and acts as a negative regulator of Toll-like receptor signaling.
IRAK3 plays a critical role in innate immunity and is implicated in immunocompromised states during sepsis.
Mutations in IRAK3 are associated with susceptibility to asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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