
Thermo Fisher Scientific CARD11 Polyclonal Antibody
CARD11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품으로, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding methionine 362 of human CARD11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11004453 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as a molecular scaffold for multiprotein complexes at specialized plasma membrane regions. It is also a member of the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). CARD11 and CARD14 proteins interact with BCL10, a positive regulator of cell apoptosis and NF-kappaB activation. Expression of CARD11 activates NF-kappaB and induces phosphorylation of BCL10.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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