Thermo Fisher Scientific Complement C3dg fragment Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 Complement C3dg fragment를 인식. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제된 액상 형태로, 안정적 저장 및 재현성 높은 결과 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Complement C3dg fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The complement factor C3 consists of an alpha and a beta chain and plays a central role in the complement cascade. It is a key component of the alternative pathway leading to the C3 convertase C3bBb, as well as the classical mannose-binding lectin pathway forming C4b2a. These convertases cleave C3 into C3a and C3b, which further degrade into C3d, C3g, and C3c. C3 acts as an acute phase protein produced by various tissues, including renal epithelial cells and hepatocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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