Thermo Fisher Scientific FDPS Recombinant Rabbit Monoclonal Antibody (005)
인간 FDPS 단백질을 인식하는 재조합 토끼 단클론 항체입니다. WB, ICC/IF, Flow, ELISA, IP 등 다양한 응용에 적합합니다. 높은 특이성과 재현성을 제공하며, 보존제가 포함되지 않은 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 |
| Flow Cytometry (Flow) | 1:25–1:100 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 005 |
| Immunogen | Recombinant Human FDPS (Farnesyl Diphosphate Synthase) protein (Met1–Lys353) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785167 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned, and the best candidates are selected for production.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin–free formulation
- Broader immunoreactivity due to rabbit immune repertoire
This antibody specifically recognizes Human FDPS (Farnesyl Diphosphate Synthase).
Target Information
The isoprene biosynthetic pathway provides cholesterol, ubiquinone, and other nonsterol metabolites. Farnesylpyrophosphate synthetase catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate.
Studies in rat liver using immunofluorescence and immunoelectron microscopy show FDPS is mainly localized in peroxisomes. Liver tissues from patients with peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy show reduced FDPS activity and impaired isoprenoid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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