
Thermo Fisher Scientific CDK8 Polyclonal Antibody
CDK8 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 인간 반응성, 마우스 및 개구리 종에도 예측 반응.
- 카탈로그번호
- A302500Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDK8 Polyclonal Antibody
Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 370 and 420 of human cyclin-dependent kinase 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, X. laevis, and X. tropicalis
Target Information
CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II. This protein is coexpressed and copurified with Cyclin C. CDK8 belongs to the cyclin-dependent kinase family, key regulators of cell cycle progression. The prototype members p34/Cdc2 and Cdk2 function late in the cycle, while Cdk4 and Cdk6 are involved in G1 to S progression. Analogous to yeast Cdk8, human Cdk8–Cyclin C complex may interact with RNA polymerase, influencing transcription mechanisms related to cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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