Thermo Fisher Scientific CD147 Polyclonal Antibody
Thermo Fisher Scientific의 CD147 Polyclonal Antibody는 인간 CD147 단백질을 인식하는 토끼 IgG 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로 고품질 검출에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 6 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 3 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 2 publications |
| ELISA | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the N-terminal region of the human EMMPRIN protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533176 |
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression, and is a member of the immunoglobulin superfamily.
CD147 is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates the cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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