Thermo Fisher Scientific PSD93 Polyclonal Antibody
PSD-93 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫드 반응성. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the mid region of PSD-93 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533171 |
Target Information
PSD-93, also known as chapsyn-110, is a plasma membrane-associated protein localized in synaptic junctions. It is uniquely expressed in Purkinje neuron cell bodies and dendrites. PSD-93 contains three PDZ domains, one SH3 domain, and an enzymatically inactive guanylate kinase (GuK) domain. PDZ-domain interactions are believed to contribute to receptor and channel clustering, influencing neuronal plasticity. PSD-93 interacts with NMDA receptors and shaker-type potassium channels via a threonine/serine-X-valine-COOH (T/SXV) motif. It also associates with neuronal nitric oxide synthase (nNOS) through PDZ-PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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