Thermo Fisher Scientific ETV5 Monoclonal Antibody (3B10)
ETV5 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 ELISA에 적합합니다. 인간 시료 반응성이 있으며, PBS buffer에 보존되어 있습니다. 연구용으로 SSC 자기재생 관련 ETV5 발현 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B10 |
| Immunogen | ETV5 (NP_004445, 181–290 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LPEPGPQQQT FAVPRPPHQP LQMPKMMPEN QYPSEQRFQR QLSEPCHPFP PQPGVPGDNR PSYHRQMSEP IVPAAPPPPQ GFKQEYHDPL YEHGVPGMPG PPAHGFQSPM
Target Information
ETS variant 5 (ETV5) is a transcription factor of the ETS family and a divergent member of the winged helix-turn-helix superfamily. It is expressed in brain, placenta, and other tissues involved in development.
Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that ETV5 is required for SSC self-renewal but not differentiation, and affected mice exhibit progressive germ cell depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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