Thermo Fisher Scientific NUP98 Polyclonal Antibody
NUP98 단백질을 검출하기 위한 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 사용 가능하며, Human 시료에 반응합니다. Protein G로 정제된 액상 항체로, -20°C 이하에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NUP98 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1:200–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Nuclear pore complex protein Nup98-Nup96 (965–1110 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.205 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091506 |
Target Information
Signal-mediated nuclear import and export occur through the nuclear pore complex (NPC), composed of approximately 50 unique nucleoporins. The 98 kDa nucleoporin (NUP98) is derived from a 186 kDa precursor that is cleaved to yield both 98 kDa and 96 kDa nucleoporins localized to the nucleoplasmic side of the NPC. Studies indicate that NUP98 functions as a docking site nucleoporin for transport substrates.
The human NUP98 gene is implicated in several chromosomal translocations associated with acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). It resides in the imprinted gene domain of 11p15.5, a critical tumor-suppressor region linked to Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and cancers of the lung, ovary, and breast. Alternative splicing produces multiple transcript variants, not all of which are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.