Thermo Fisher Scientific BID Monoclonal Antibody (OTI1G10), TrueMAB
Human BID 단백질을 인식하는 마우스 단클론 항체로, Western Blot, IHC, ICC에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/1% BSA/50% 글리세롤 버퍼에 보관됩니다. 세포사멸 연구용으로 최적화된 연구 전용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G10 |
| Immunogen | Full length human recombinant protein of human BID produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It belongs to the BCL-2 family of cell death regulators and mediates mitochondrial damage induced by caspase-8 (CASP8). Upon CASP8 cleavage, the COOH-terminal fragment translocates to mitochondria, triggering cytochrome c release and apoptosis. BID acts as a direct molecular link between caspase-8 activation and mitochondrial death pathways.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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