Thermo Fisher Scientific OCT-4 (POU5F1) (Germ Cell Tumor Marker) Recombinant Rabbit Monoclonal Antibody (OCT4/8098R)
인간 OCT-4/POU5F1 단백질을 인식하는 재조합 토끼 단일클론 항체. 생식세포 종양 마커로 IHC(P) 검증됨. 단백질 A/G 정제, 4°C 보관. 줄기세포 연구 및 분화 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OCT4/8098R |
| Immunogen | Recombinant fragment of human OCT-4/POU5F1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Raji or U-937 cells, human seminoma, or testicular carcinoma
- Cellular Location: Nucleus
Target Information
POU5F1, also known as Oct-4, is a maternally expressed octamer-binding transcription factor important in early embryonic development. Its role in maintaining pluripotency makes it valuable for stem cell research and regenerative medicine. Expression of POU5F1 with Sox2, Klf4, Lin28, and c-Myc enables the generation of induced pluripotent stem (iPS) cells, offering potential applications in cell replacement therapies and disease modeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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