Thermo Fisher Scientific Phospho-IKK gamma (Ser85) Polyclonal Antibody
Human IKK gamma 단백질의 Ser85 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 고순도 액상 형태로 제공. 연구용으로 NF-kappaB 신호전달 관련 단백질 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IKBKG (Accession Q9Y6K9), corresponding to amino acid residues around phosphorylated Ser85 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816519 |
Product Specific Information
Antibody detects endogenous levels of IKK gamma only when phosphorylated at Serine 85.
Target Information
IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways.
Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies.
Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-105046_IKK_gamma_Q9Y6K9-1_Rabbit_PDP.jpeg)
(이미지 파일명: PA5-105046_IKK_gamma_Q9Y6K9-1_Rabbit.svg)
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