Thermo Fisher Scientific SP100 Polyclonal Antibody
인간 SP100 단백질에 반응하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 고순도 Affinity chromatography로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며, SP100 핵소체 관련 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SP100 (Accession P23497), corresponding to amino acid residues E521–Q571 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903357 |
Product Specific Information
Antibody detects endogenous levels of total SP100.
Target Information
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies.
PML and SP100 are covalently modified by the SUMO-1 modifier, which is crucial to nuclear body interactions.
The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation.
Alternatively spliced variants have been identified for this gene, one of which encodes a high-mobility group protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-118857_SP100_P23497-1_Rabbit.svg, PA5-118857_SP100_P23497-1_Rabbit_PDP.jpeg)
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